Dr. Xing assisted the innovative project of mental illness diagnosis and treatment

Background information

The prevalence of mental illness continues to climb as social development and stress increases. According to the China Mental Health Survey, the lifetime weighted prevalence rate of six categories of mental disorders in China is as high as 16.6 percent. Schizophrenia, depression and other mental disorders have become a heavy burden on society, families and individuals. However, the biological pathogenesis of mental illness is not clear, which has become an urgent problem to be solved by the global medical community.

As the largest psychiatric hospital chain group in China, the hospital has been committed to promoting the improvement of the diagnosis and treatment of mental diseases. In order to strengthen the scientific research strength and innovative diagnosis and treatment ability in this field, the hospital actively seeks high-end talents and promotes the deep integration of scientific research and clinical diagnosis and treatment by introducing international top scientists.

Dr. Xing graduated from Massey University in New Zealand, majoring in animal science. He has more than 20 years of experience in basic research on neurotrauma. He has conducted research in the Institute of National Institutes of Health (NIH) (NIMH) and other well-known medical institutions, focusing on the molecular biology of neurological diseases. He has made outstanding achievements in the research of senile dementia, schizophrenia, depression and other mental diseases. He has published more than 80 SCI papers, 12 of which have been published in Q1 journals, including Nature Neuroscience and Molecular Psychiatry.

In recent years, Dr. Xing has focused on the innovative diagnosis and clinical verification of mental illness, especially in making important breakthroughs in the study of biomarkers of schizophrenia and traumatic stress disorder (PTSD).

Project cooperation content

1. Work objectives

Dr. Xing will combine his own advantages, focus on the two-way research of social and biological etiology of mental diseases, explore the biological mechanism of multiple mental diseases, including schizophrenia and depression, explore the biomarkers of early diagnosis and targeted intervention goals, and provide a basis for the formulation of scientific intervention programs.

2. Main ways

the first year:

· With the help of Dr. Xings international resources, the American collaborative model of mental illness research was systematically introduced.

· Expand the existing temporary scientific research team to more than 20 people, and establish a molecular biomedical laboratory.

· Carry out medical research combining basic and clinical research to promote the rapid transformation of scientific research results.

Second to third year:

· Specimens from clinical cases including schizophrenia and depression were collected and a database was established.

· Screening of biomarkers for psychiatric disorders and study of animal models of disease.

· Design and conduct clinical trials of innovative biomarker-based intervention programs.

Fourth to fifth years:

· Using screen-detected biomarkers to achieve early rapid diagnosis and treatment of psychiatric disorders.

· Aiming at the key topics in the field of international psychiatry, I have published high-level papers and applied for related patents.

3. Expected contribution

Technical contributions:

· The first year: cultivate a group of excellent clinical and scientific research compound talents, build a municipal or above key laboratory.

· Year 2-3: Establish the provincial key laboratory, and release the database of accurate diagnostic biomarkers.

· Year 4-5: Establish the national key laboratory of mental illness research, and promote the innovative diagnosis and treatment methods of early diagnosis and intervention of mental illness.

Industrialization contribution:

· Develop a set of early diagnosis and intervention system of mental illness to alleviate the limitations of drug treatment.

· From the third year, it is expected to increase the annual revenue of the enterprise by 150 million yuan, and enhance the influence of Corning Hospital in the field of mental illness diagnosis and treatment at home and abroad.

Existing foundation and support measures

The hospital has 23 self-owned hospitals, including an Internet hospital, with a total of more than 7,000 beds and annual revenue of more than 1 billion yuan. The research platform includes cell and molecular biology laboratory, mental disease model animal laboratory, etc., with a total research space of more than 2,000 square meters.

Support measures:

1. Salary and scientific research conditions: annual salary of 900,000 yuan, 500 square meters of laboratory and 30 million yuan of start-up capital.

2. Team support: equipped with a 15-person R & D team, including 5 doctors.

3. Living security: to provide 120 square meters of talent apartment, and give priority to the employment of expert spouses.